Gene

ptbp1b

ID

ZDB-GENE-030131-9796

Name

polypyrimidine tract binding protein 1b

Symbol

ptbp1b Nomenclature History

Previous Names

cb363 (1)
id:ibd2901
im:7145323
sb:cb363 (1)
si:ch211-262i1.1
wu:fa04b05
wu:fb16f08
wu:fc58e03

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have mRNA binding activity. Predicted to be involved in negative regulation of mRNA splicing, via spliceosome; regulation of cell differentiation; and regulation of translation. Predicted to localize to nucleus. Is expressed in several structures, including EVL; axis; mesoderm; nervous system; and pronephric duct. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb363 (10 images)
IMAGE:7145323 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptbp1b Human Ortholog

No data available

Associated With ptbp1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR021790	PTBP1-like, RNA recognition motif 2
Domain	IPR035000	PTBP1, RNA recognition motif 1
Family	IPR006536	HnRNP-L/PTB
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	HnRNP-L/PTB	Nucleotide-binding alpha-beta plait domain superfamily	PTBP1-like, RNA recognition motif 2	PTBP1, RNA recognition motif 1	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A8M2B222 InterPro	547
UniProtKB:A0A8M3BDK1 InterPro	518
UniProtKB:F1QKG2 InterPro	564

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	ptbp1b-205 (1) Ensembl	Ensembl	824 nt	Select Tool
mRNA	ptbp1b-201 (1) Ensembl	Ensembl	3,619 nt	Select Tool
mRNA	ptbp1b-202 (1) Ensembl	Ensembl	311 nt	Select Tool
mRNA	ptbp1b-203 (1) Ensembl	Ensembl	341 nt	Select Tool
mRNA	ptbp1b-206 (1) Ensembl	Ensembl	765 nt	Select Tool
ncRNA	ptbp1b-004 (1) Ensembl	Ensembl	801 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations